منابع مشابه
Protection of renal damage by HMG-CoA inhibitors: A comparative study between atorvastatin and rosuvastatin
Objective(s): Hypercholesterolemia is a common metabolic disorder in developing and developed countries and is associated with the increased rates of chronic kidney disease (CKD). Statin therapy could reduce cholesterol synthesis as well as progression of CKD. Diversity between statins causes variety in pharmacokinetics and pharmacodynamics and also their pleiotropic e...
متن کاملAtherosclerotic renal artery stenosis, ACE inhibitors, and avoiding cardiovascular death.
Correspondence to: Dr John Main, Renal Unit, James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, UK; [email protected] _________________________ A therosclerotic renal artery stenosis (ARAS) has become topical since the development of percutaneous angioplasty and stenting. Studies defining the place for intervention have been difficult to perform and inconclusive. However, ...
متن کاملACE inhibitors and appearance of renal events in hypertensive nephrosclerosis.
Nephrosclerosis constitutes a major cause of end-stage renal disease. Independently of blood pressure control, ACE inhibitors (ACEIs) are considered to be more nephroprotective than other antihypertensive agents. We have reviewed the long-term evolution of renal function in our series of essential hypertensive patients diagnosed as having nephrosclerosis when first seen in our unit. The analysi...
متن کاملACE Gene Polymorphism and renal responsiveness to ACE inhibitors in IgA nephropathy patients
We examined the renal responsiveness to ACE inhibitor in IgA nephropathy (IgAN) patients according to the grouping of ACE gene polymorphism. Sixty one patients diagnosed as IgAN by renal biopsy and prescribed with ACE inhibitors were enrolled. Genomic DNA was extracted from whole blood and PCR was performed. The I/D polymorphism was determined by the presence of the 287 bp fragment in intron 16...
متن کاملACE, ACE inhibitors, and other JNK.
The renin-angiotensin system (RAS) plays a pivotal role in the regulation of blood pressure, volume homeostasis, vascular function, and cell growth. In what is considered the classic RAS, renin is released from juxtaglomerular cells of the kidney into the circulation where it converts angiotensinogen from the liver to angiotensin I. Angiotensin I is subsequently hydrolyzed by a peptidyl dipepti...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1997
ISSN: 0007-0912
DOI: 10.1093/bja/78.4.477